The literature review article "The Potential of Resveratrol as an Anticancer Agent" published in 2025 summarizes the benefits and...

The literature review article "The Potential of Resveratrol as an Anticancer Agent" published in 2025 summarizes the benefits and potential of resveratrol as an anticancer agent as follows:

Benefits and mechanism of anti-cancer action of resveratrol

Resveratrol is a natural polyphenolic compound that plays a unique role in anticancer activity through a variety of complex biological mechanisms, including:

● Inhibits the growth and spread of cancer cells. (Antiproliferative): Resveratrol can interfere with communication signals within cancer cells. This effectively stops the division cycle and inhibits the expansion of tumor cells.

● Induces cancer cell death. (Proapoptotic): One of the key mechanisms is to stimulate the self-destruction process of cancer cells (Apoptosis), which helps eliminate abnormal cells from the body.

● Resist the creation of new blood vessels that feed cancer. Antiangiogenic: Tumors need new blood vessels to carry nutrients in order to grow. Resveratrol has the ability to block these angiogenic processes. This causes the tumor to lack nutrients and grow more slowly.

● Reduce inflammation within the body. Anti-inflammatory: This compound can inhibit key inflammatory pathways (such as NF-κB), which are important stimulating factors in the formation and progression of many types of cancer.

● Oxidative Stress Regulation: Resveratrol helps regulate free radical levels within cells to an optimal state. Helps reduce damage to DNA that can lead to cancer.

● Epigenetic Modifications: This substance plays an important role in regulating the expression of genes involved in cancer. By helping to organize the work of genes to return to normal.

● Enhances treatment efficacy: Resveratrol has the potential to work well with standard chemotherapy drugs. By helping to increase efficiency in destroying cancer cells. and reduces the ability of cancer cells to resist drugs Makes treatment more hopeful