Research article from PMC titled "A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemot...

A research article from PMC titled "A Review of Resveratrol as a Potent Chemoprotective and Synergistic Agent in Cancer Chemotherapy" summarizes key points about the role of Resveratrol (Resveratrol), a plant extract. (found mainly in red grapes and red wine) in the treatment of cancer as follows:

​1. Role in being a cancer prevention agent (Chemoprotective Agent)

Prevention: Resveratrol can inhibit the cancer process at all stages. From the beginning (Initiation), promotion (Promotion) to spread. (Progression)

​Mechanism: Helps reduce inflammation through inhibiting the COX-2 enzyme and protecting against free radicals that damage cellular DNA.

​2. Working together with chemotherapy drugs (Synergistic Effect)

​This is the highlight of this article, which states that Resveratrol enhances the effectiveness of chemotherapy drugs. (Chemotherapy) of many types such as:

​● Increases the sensitivity of cancer cells to drugs: Helps drug-resistant cancer cells. returned to respond better to chemotherapy (Chemosensitization)

● Reduce side effects: Helps protect normal cells from the toxic effects of chemotherapy, such as reducing toxic effects on the heart, kidneys, and immune system. without reducing the effectiveness of the drug in killing cancer

​3. Molecular mechanism of action

Resveratrol interferes with the vital signs of cancer cells in several ways, such as:

- Stimulate cell death (Apoptosis): causing cancer cells to destroy themselves.

- Inhibits the creation of new blood vessels (Anti-angiogenesis): Breaks the cycle of food that feeds cancer tumors.

- Inhibits cell cycle: causes cancer cells to stop dividing.

​Overview summary

Resveratrol has great potential to be used "alongside" traditional treatment. To increase your chances of healing and reduce your suffering from medication side effects.