The National Institutes of Health (NIH) lists periodontal disease as a public health problem. It is estimated that 42.2 percent of American adults with...

The National Institutes of Health (NIH) lists periodontal disease as a public health problem. It is estimated that 42.2 percent of American adults over 30 years of age have periodontal disease (gingivitis) and 59.8 percent of all adults over 65 years of age. Periodontal disease is an inflammatory disease. The researchers therefore wanted to test whether resveratrol which is an anti-inflammatory dietary supplement Will it help improve the clinical indicators of this disease? Researchers have found it beneficial when used as an adjunct to treatment for periodontal disease.

Summary of research articles on

“Impact of resveratrol supplementation on clinical parameters and inflammatory markers in patients with chronic periodontitis: a randomized clinical trial”

Research overview

This was a randomized, double-blind, placebo-controlled trial.

Study of patients with chronic periodontitis (chronic periodontitis)

Number of people: 40 people

Everyone receives standard treatment. (Scaling away tartar/non-surgical treatment)

Divided into 2 groups:

Experimental group: received resveratrol supplementation

Control group: received placebo

Duration: 4 weeks

Indicators studied

1. Oral clinical values

Depth of the gingival sulcus (PD)

Dental adhesion level (CAL)

Plaque Index (PI)

Bleeding Index (BI)

2. Inflammation indicators (in saliva)

IL-1β

IL-8

Important results

Plaque Index (PI) decreased significantly. in the group receiving resveratrol compared to placebo

Other variables were not significantly different, including:

Depth of the gingival sulcus (PD)

Adhesion loss (CAL)

Bleeding (BI)

IL-1β and IL-8 levels

Summary of findings

Resveratrol can help reduce plaque in the mouth.