Summary of the article

The phenolic components extracted from mulberry fruits as bioactive compounds against cancer: A review

Published in the journal Phytotherapy Research in 2023.

This article is a review of research on Phenolic compounds found in Mulberry fruits which have the potential to help Prevent and fight cancer

Important substances found in mulberries

The main active ingredients found include:

Flavonoids (flavonoids)

Such as Kuwanons, Moracinflavans, Moragrols, Morkotins.

Anthocyanins (Anthocyanins)

It is a reddish-purple substance found mostly in ripe fruits.

Phenolic acids

Alkaloids (alkaloids)

Benzofurans and Chalcones

These substances are a group of polyphenols that have high biological activity. Especially in terms of antioxidants and fighting cancer cells.

Anti-cancer mechanism

The article states that these substances help fight cancer through several mechanisms, such as:

1. Antioxidants (Antioxidant)

Helps reduce oxidative stress, which is a major cause of cancer.

2. Stimulate the death of cancer cells (Apoptosis)

Flavonoids and chalcones can stimulate cancer cells to undergo natural death.

Without destroying normal cells like chemotherapy drugs

3. Inhibits the division of cancer cells

Helps reduce the number of cancer cells in many types such as

breast cancer

Liver cancer

Colon cancer

blood cancer

lung cancer

4. Reduce inflammation (Anti-inflammatory)

Chronic inflammation is one of the factors that trigger cancer.

Polyphenols in mulberries help reduce inflammation at the cellular level.

Highlights of Anthocyanins

The article states that

Absorbed quickly into the body within 15–50 minutes.

Completely eliminated within 6–8 hours.

Therefore, it is suitable to receive continuously from dietary supplements.

Important conclusions

Mulberries are a great source of polyphenols that have the potential to help protect against cancer.

especially through

Antioxidants

Reduce inflammation

Inhibits the division of cancer cells

stimulate apoptosis

therefore has a high tendency to develop into

Functional food

Nutraceutical

dietary supplements

Products to delay aging and prevent chronic diseases

Brief summary:

**“Mulberry is not just a fruit. But it is a source of high levels of natural anti-cancer substances.”**