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“Resveratrol (RV): A pharmacological review and call for further research” from ScienceDirect

Overview of resveratrol (Resveratrol) is a polyphenol group substance found in red grapes and mulberries, etc.

It received attention because Various biological activities such as antioxidant, anti-inflammatory, and anti-aging.

Main pharmacological effects

This article compiles many studies and reveals that resveratrol has important properties including:

1. Against chronic diseases in many systems

Heart and blood vessels: Reduces platelet adhesion. Helps prevent hardened arteries

Brain and nervous system: has neuroprotective effects. Helps reduce the degeneration of nerve cells.

Diabetes: Helps control sugar levels and glucose metabolism.

2. Anticancer (Antitumor)

Inhibits the growth of cancer cells

Regulates the processes of apoptosis (cell death) and inflammation.

3. Anti-obesity

Reduce fat accumulation

Stimulates fat burning (lipolysis)

4. Antimicrobial

Inhibits pathogenic bacteria such as

E. coli, Staphylococcus aureus

Mechanism: Interferes with bacterial energy production systems (ETC and ATPase).

Mechanism of action

Resveratrol works through several pathways such as:

Reduce oxidative stress (oxidative stress)

Control inflammation (inflammation)

stimulate or inhibit cell death pathways

In summary, it is a substance that "works on many systems simultaneously" (multi-target compound).

Safety

Overall, it is considered safe and well tolerated.

It has the potential to be used as:

Supplements (nutraceutical)

Complementary drug

Brief summary

Resveratrol is a natural substance with great potential in preventing and treating many diseases (heart, brain, cancer, diabetes) through antioxidant and anti-inflammatory mechanisms.