“Resveratrol, a Molecule with Anti-Inflammatory and Anti-Cancer Activities: Natural Product to Chemical Synthesis” ตี...

Summary of the article “Resveratrol, a Molecule with Anti-Inflammatory and Anti-Cancer Activities: Natural Product to Chemical Synthesis” published on PubMed in 2021.

Overview of Resveratrol

It is a substance in the natural polyphenol group, found mainly in red grapes and mulberries. It acts on plants to protect against fungi and microorganisms.

In humans, this substance has outstanding properties such as

anti-inflammatory

Antioxidants

Anti-cancer

Important biological activities

1. Anti-inflammatory (Anti-inflammatory)

Reduce the activity of inflammatory substances in the body

Balancing the immune system

Inhibits the pathway that causes inflammation

Therefore, it has the potential to help reduce chronic diseases such as diabetes and heart disease.

2. Anti-cancer

Resveratrol can:

Stimulates cancer cells to die by apoptosis

Inhibits the growth of cancer cells

Reduce the progression and spread of cancer.

It works through several mechanisms at the cellular level, such as

Akt/mTOR pathway

p38 MAPK pathway

3. Protect cells (Cytoprotective)

Reduce damage from oxidative stress

Helps slow down cell degeneration

It plays a role in aging and neurological diseases.

Summary of the main points of the article

Important Insight

“Natural substances but work at a medicinal level”

“It is being developed industrially → It is not just a general dietary supplement.”