Academic matters

Summary of academic articles on

“Cutting-edge extraction technologies for anticancer compounds from ethnomedicinal mulberry: A molecular review in cancer management” published 2025

"State-of-the-art anticancer extraction technology from mulberry (mulberry), a traditional herb: a molecular review in cancer management."

Overview of the article

This article is a review paper that collects knowledge about

Important substances from “Mulberry (Morus spp.)”

Molecular mechanisms of cancer resistance

modern extraction technology (cutting-edge extraction)

by emphasizing the role of Mulberry in Molecular prevention and treatment of cancer

1. Important substances in mulberry (Phytochemicals)

Mulberry contains many groups of biologically active substances such as

Flavonoids

Polyphenols

Anthocyanins

Alkaloids

Polysaccharides

These substances have effects:

Antioxidants (antioxidant)

Reduce inflammation

Boost immunity

Helps control sugar levels

2. Anti-cancer mechanisms (Molecular mechanisms)

Mulberry substances affect cancer cells in many ways, including:

Main mechanism

Inhibits cell division (anti-proliferation)

Stimulates the death of cancer cells (apoptosis)

Stop the cell cycle (cell cycle arrest)

Inhibit the spread (anti-metastasis)

Destroys cells through mitotic catastrophe.

It means:

Mulberry does not act on just one site, but “attacks multiple mechanisms simultaneously.”

3. Use with chemotherapy drugs

The article points out:

Substances from mulberry can Enhance the effects of chemotherapy drugs

Reduce drug toxicity

Increase treatment efficiency

This concept is called the synergistic effect.

4. Modern extraction technology (Cutting-edge extraction)

The article emphasizes that “Extraction technology” is the key.

The technology mentioned

Enzyme-assisted extraction

Microwave-assisted extraction

Ultrasound-assisted extraction

Pulsed electric field (PEF)

Deep eutectic solvents (DES)

Advantages of new technology

Get more concentrated important substances

Reduce the use of hazardous chemicals (green extraction)

Maintains intact molecular structure

increase bioavailability

Conclusion: New technology helps “Draw out anti-cancer substances more efficiently than before.”

5. Medical importance

mulberry is ethnomedicinal plant (local herbs)

Has the potential to develop into:

cancer medicine

functional food

nutraceutical

Summary:

Mulberries are a potent source of anti-cancer compounds. It works by several mechanisms at the cellular level. And modern extraction technology increases the efficiency of using these substances for medical use.