Influence of resveratrol on cardiovascular health in chronic kidney disease.

Influence of resveratrol on cardiovascular health in chronic kidney disease.

Influence of Resveratrol on the Cardiovascular Health Effects of Chronic Kidney Disease

Abstract: Cardiovascular disease (CVD) is closely related to chronic kidney disease (CKD), and patients with CKD are at high risk of cardiovascular death. Traditional cardiovascular risk factors cannot be explained. Higher risk of cardiovascular disease in patients with chronic kidney disease. And standard cardiovascular intervention has failed to reduce the death rate of CKD patients. Non-traditional factors related to minerals and vitamin D Metabolic abnormalities provide some explanation for the increased risk of cardiovascular disease. The non-analyzable toxins indoxyl sulfate (IS) and p-cresol sulfate (PCS)—produced in the liver by intestinal microorganisms—cause kidney and vascular disorders. Plasma trimethylamine-N-oxide (TMAO)—depending on gut microbes Dietary metabolites of L-carnitine and choline—increased in CKD and associated with vascular disease, resulting in a shortened lifespan. Therefore, adjusting the microflora in the colon can increase the chances for patients with chronic kidney disease. Prophylactic management of metabolic syndrome, anemia, and metabolic abnormalities is recommended. cardiovascular disease In patients with chronic kidney failure using resveratrol (RSV), which is a dietary supplement. It is beneficial for patients with coronary artery disease and chronic kidney disease. This article discusses the benefits of resveratrol. to biological responses Pathophysiological and clinical, including improving the integrity of the intestinal epithelium. Balancing the microorganisms in the intestines and reduction of hepatic synthesis of IS, PCS, and TMAO in patients with cardiovascular disease and chronic kidney disease.

https://www.mdpi.com/1422-0067/21/17/6294

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