Resveratrol is extracted from the mulberry in the Resveratrol product. Dr.Vee has a lot of research explaining it. Biomolecular mechanisms (Molecula...

Resveratrol is extracted from the mulberry in the Resveratrol product. Dr.Vee has a lot of research explaining it. Biological molecular mechanisms (Molecular Mechanisms) that can help reduce the risk of lung cancer from PM2.5 dust can be explained in sequence as follows:

Biomolecular mechanism of resveratrol (Resveratrol) extracted from mulberry To prevent lung cancer from PM2.5

Inhibits the generation of free radicals (Oxidative Stress)

PM2.5 → enters the lungs' air sacs → stimulates the production of ROS (Reactive Oxygen Species)

ROS causes

damaged DNA

Inflammatory cells

stimulate cancer

Resveratrol is extracted from mulberry.

Stimulates the antioxidant system in cells

Increase the functionality of

SOD (Superoxide dismutase)

Catalase

Glutathione peroxidase

Results

Reduce ROS

Reduce DNA damage of lung cells

Reduce cell mutation

Stimulates the Nrf2 Pathway (cell defense system)

PM2.5 weakens the cell's defense system.

Resveratrol stimulates important proteins.

Nrf2 (Nuclear factor erythroid 2–related factor 2)

When Nrf2 is stimulated, it increases enzyme production.

HO-1

NQO1

GST

Results

Increase the Detox system of cells

Eliminate toxins from PM2.5

Prevent cancer

Inhibit inflammation at the cellular level (Anti-inflammatory)

PM2.5 dust causes chronic inflammation in the lungs.

stimulate

NF-κB pathway

cause

TNF-α

IL-6

IL-1β

which is a stimulant for cancer.

Resveratrol

inhibit

NF-κB signaling

Results

Reduce inflammation in the lungs

Reduce the microenvironment of cancer

Stimulates abnormal cell death (Apoptosis)

Cells that are destroyed by PM2.5 may become cancer cells.

Resveratrol stimulates

p53 tumor suppressor gene

and add

Bax

Caspase-3

Ready to reduce

Bcl-2

Result

Abnormal cells are eliminated.

Reduce the chance of cancer

Inhibits the creation of cancer blood vessels. (Anti-angiogenesis)

If cancer has already occurred

Resveratrol can

inhibit

VEGF

HIF-1α

make

Cancer tumors cannot form blood vessels.

Limit cancer growth

Adjust the function of SIRT1 (Longevity Gene)

Resveratrol Stimulant

SIRT1

make

DNA repair

Reduce inflammation

Slow down the degeneration of lung cells

Summary of important mechanisms

PM2.5 → ROS ↑ → DNA damage → inflammation → cancer

Resveratrol is extracted from mulberry.

Works on 6 main mechanisms

>> Antioxidants

>> Stimulates Nrf2 detox pathway

>> Inhibits NF-κB inflammation

>> stimulate apoptosis

>> Inhibits angiogenesis

>> Stimulates SIRT1 to repair cells

Thus helping to reduce the risk of lung cancer from PM2.5 dust.