Back to Articles
เรสเวอราทรอลเป็นสารโพลีฟีนอลจากธรรมชาติที่ช่วยชะลอความแก่โดยการกำหนดเป้าหมายกลไกสำคัญ เช่น การกระตุ้นเซอร์ทูอิน 1 (SI...

Resveratrol is a natural polyphenol that slows aging by targeting key mechanisms such as stimulating sirtuin 1 (SI...

#anti-cancer#neuroprotective#cardiovascular#anti-aging#anti-inflammatory#diabetes-metabolic#organ-protection

Resveratrol is a natural polyphenol that delays aging by targeting key mechanisms such as sirtuin 1 (SIRT1) activation, AMPK activation, and mTOR inhibition. It acts as a powerful anti-inflammatory and antioxidant. Helps reduce mitochondrial abnormalities. Reduce stress from free radicals and control cell death These effects help prevent age-related diseases. Including heart disease and blood vessels Neurodegenerative diseases (AD, PD), type 2 diabetes mellitus (T2DM), and obesity

Important mechanisms of aging and action of resveratrol

Nutrient Sensing Pathway: Resveratrol mimics calorie restriction by stimulating SIRT1 and AMPK, which improves metabolic efficiency and reduces insulin resistance.

Mitochondrial function: enhances the formation and function of mitochondria through the AMPK-mTOR pathway, reducing the production of free radicals (ROS).

Reduces inflammation: Resveratrol inhibits inflammatory mediators such as NF-κB and TNF-α, reducing chronic inflammation associated with aging. (inflammation caused by aging)

Cell Degeneration: Helps control cell death and cell deterioration. Extending cell lifespan in various models

Effective in preventing age-related diseases

Cardiovascular disease: Resveratrol promotes the elasticity of the aorta. Improves the function of the blood vessel lining. and lowers blood pressure by reducing oxidative stress and inflammation in the lining of blood vessels.

Neurodegenerative diseases: Helps prevent Alzheimer's and Parkinson's diseases by reducing neuroinflammation and increasing autophagy.

Metabolic syndrome and diabetes: improves insulin sensitivity and reduces obesity-related indicators.

Cancer and bone health: Study points to potential to inhibit tumor growth and prevent bone loss. Osteoporosis (osteoporosis) by modulating mesenchymal stem cells in the bone marrow