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From the picture of resveratrol (Resveratrol), which is a phenolic compound found in the skin of red grapes and mulberries. There are various mechanisms of action...
From the picture of resveratrol (Resveratrol), which is a phenolic compound found in the skin of red grapes and mulberries. It has a variety of mechanisms of action and has a beneficial effect on various systems in the body as follows:
1. Anti-cancer effect (Anticarcinogenic & Anti-neoplastic)
Resveratrol inhibits the birth and growth of cancer cells in several ways:
Inhibits the activation of toxins: inhibits the Metabolic Activation process (both Phase I and Phase II), causing carcinogens to be unable to act.
Anti-gastric cancer: inhibits DNA synthesis of cancer cells (Gastric adeno carcinoma), inhibits normal cell death (Apoptosis) and inhibits pKc group of enzymes that promote tumor growth.
2. Antioxidant Activity
Resveratrol is a powerful antioxidant:
Stimulates protective enzymes: Helps increase levels of Glutathione Peroxidase, Glutathione S-transferase and Glutathione reductase, which are the body's natural defense systems.
Maintain good fats: Helps prevent the destruction of polyunsaturated fatty acids. (Preservation of PUFA)
3. Effects on the cardiovascular system (Cardiovascular Effect)
Reduce platelet aggregation: Helps reduce Platelet Aggregation, which reduces the risk of blood clots.
Protects the heart: Helps reduce damage from ischemic reperfusion damage and reduces bad fat oxidation (LDL oxidation).
4. Anti-inflammatory and anti-arthritis effects (Anti-Arthritis)
Inhibits enzymes and proteins that cause inflammation, such as COX, LOX, and NF-kB, which are the main causes of pain and inflammation in joints.
5. Anti-diabetic effect (Anti-Diabetic)
Stimulates the activity of Sirt 1 (Histone deacetylase), which requires NAD+. Sirt 1 plays an important role in regulating energy balance and increasing sensitivity to insulin.
6. Enzyme Inhibitor
Acts to inhibit enzymes that produce free radicals such as Superoxide dismutase, Lipo-oxygenase, and Peroxidase, as well as blocking the activity of PDE (Phosphodiesterase).
Short summary: Resveratrol works holistically. Focusing on "reducing inflammation, antioxidants and protect cells" from degeneration and various toxins