Cerebrovascular disease (Stroke) and coronary artery disease (Coronary Artery Disease) even though they show symptoms in different organs. But there is a starting point...

Cerebrovascular disease (Stroke) and coronary artery disease (Coronary Artery Disease) even though they show symptoms in different organs. But it all started from the same cause. Deterioration of the inner blood vessel wall (Endothelial Dysfunction)

A summary of the mechanisms of disease and the methods by which natural extracts can help restore them is easy to understand as follows:

​1. Cause: When the "blood vessel wall" deteriorates.

The innermost layer of the blood vessel wall (Endothelium) acts like A "smart membrane" that controls blood vessel elasticity and prevents blood from clotting When we get older or have negative factors such as high blood sugar, high blood pressure, or accumulated free radicals The following process will occur:

​Chronic inflammation: Small wounds form in the blood vessel walls. and lose flexibility

Accumulation of fat (Plaque Formation): Bad cholesterol (LDL) gets inserted into the scars of the artery walls. until it becomes fat scale

​Constriction: When the slag deposit becomes thicker. It becomes more difficult for blood to flow through the heart or brain. If this slag breaks Will cause sudden blood clots. Leads to heart attack or paralysis.

​2. Regeneration Mechanism: Mitochondria are the "Key"

Blood vessel wall cells need a lot of energy to repair themselves. This energy is generated from Mitochondria or the power plant of the cell.

If the mitochondria are damaged Blood vessel wall cells die and are unable to repair themselves. Increasing the number and efficiency of mitochondria (Mitochondrial Biogenesis) is therefore the heart of blood vessel regeneration.

​3. The role of "Resveratrol" from mulberry

Resveratrol It is a polyphenol phytochemical found in berry fruits, including mulberry, which has an interesting mechanism of action at the cellular level as follows:

​Stimulating the anti-aging gene (SIRT1)

Resveratrol turns on a gene called SIRT1, which is like This gene sends signals to the PGC-1α protein, which is a key player in cell repair. "Create new mitochondria" to replace old ones that have deteriorated.

Effects on blood vessels:

​Increases repair energy: When there are more mitochondria Blood vessel wall cells have more energy to heal wounds and reduce inflammation.

​Increase Nitric Oxide secretion: Helps blood vessels expand well. Lower blood pressure

Antioxidants: Reduce cell damage from sugar and fat in the blood.

​Trivia: The extraction of resveratrol from mulberries is unique. Because mulberry also has substances "Anthocyanin" that enhances the effect of protecting blood vessels along with resveratrol.