Thai people have a lot of fatty liver. It can be found in up to 25-30% of the population, or about 1 in 4, and many people don't know it. Which causes Sia...

Thai people have a lot of fatty liver. It can be found in up to 25-30% of the population, or about 1 in 4, and many people don't know it. Which causes the risk of hepatitis, cirrhosis and liver cancer easily. Because the first stage of fatty liver often has no symptoms.

Important statistics:

Commonly found: up to 1 in 4 Thai people.

Unknowingly: 25-30% of Thai people have this condition without knowing it.

Diabetics: Nearly half of people with diabetes (about 50%) also have fatty liver disease.

Risk: 1 in 4 people with fatty liver will develop hepatitis, cirrhosis, or liver cancer.

Why is this a concern?

Silent disease: In the early stages, there are no symptoms. But when you realize The liver may have already suffered extensive damage.

Develops into liver disease: May lead to cirrhosis and liver cancer. Liver cancer is the number 1 most common cancer in Thai people.

Fatty Liver (Fatty Liver) and SGOT / SGPT values

Fatty liver is caused by the accumulation of triglycerides in the liver cells.

When liver cells are damaged or inflamed

→ The enzymes SGOT (AST) and SGPT (ALT) leak into the bloodstream. SGPT (ALT) in particular is considered a relatively specific indicator of liver injury.

Dr.Vee resveratrol is extracted from mulberry. How does it work on fatty liver?

Reduce fat accumulation in liver cells (Anti-lipogenesis)

Resveratrol affects the regulation of genes involved in fat production, including:

Inhibits SREBP-1c → Reduces the creation of new fatty acids.

Reduce Triglyceride accumulation in hepatocyte (liver cells)

Results:

Fat in the liver decreases.

Liver cell stress is reduced.

→ SGOT / SGPT has a downward trend.

Stimulates fat burning through AMPK enzyme.

Resveratrol stimulates an important enzyme called

AMPK (AMP-activated protein kinase)

which is like “The body's energy-burning switch”

AMPK helps:

Increases β-oxidation (fat burning)

Reduce fat accumulation in the liver

Balancing cellular energy

Effects on liver enzyme values:

Liver cells work more efficiently.

SGOT/SGPT leakage decreased

Reduce liver inflammation (Anti-inflammatory)

Fatty liver often leads to cellular inflammation.

Resveratrol helps:

Inhibits NF-κB pathway

Reduce the secretion of inflammatory substances such as TNF-α, IL-6.

When inflammation subsides:

Less liver cell damage

SGOT / SGPT therefore decreased accordingly.

Reduce Oxidative Stress (Antioxidant effect)

Fatty liver causes:

High free radicals (ROS)

Damaged liver cell membranes

Resveratrol extracted from mulberry:

It is a polyphenol antioxidant.

Increase the activity of antioxidant enzymes such as

SOD

Catalase

Glutathione peroxidase

Results:

Liver cell membranes become stronger.

Enzymes do not leak into the blood.

→ SGOT / SGPT values tend to improve.