The glomerular filtration rate (eGFR) of Mr. Suthee, aged 68 years, last measured at 97.5 ml/min/1.73m^2. Equivalent to a 30 year old person (after taking...

The glomerular filtration rate (eGFR) of Mr. Suthee, aged 68 years, last measured at 97.5 ml/min/1.73m^2. Equivalent to a 30 year old person (after taking only Dr. Vee resveratrol)

The glomerular filtration rate (eGFR: estimated Glomerular Filtration Rate) increased after continuous intake of mulberry resveratrol extract. This can be explained by several biological mechanisms as follows.

1. Resveratrol reduces inflammation in the kidneys.

Resveratrol is a powerful polyphenol. anti-inflammatory (anti-inflammatory) clearly by inhibiting the activity of NF-κB and COX-2 enzymes that trigger chronic inflammation in the kidneys.

> When inflammation decreases The remaining kidney cells will function better. Resulting in improved eGFR filtration values accordingly.

2. Protect kidney cells from free radicals.

People with decreased kidney function often experience high oxidative stress — which resveratrol can help with.

Increase levels of antioxidant enzymes such as SOD, catalase, glutathione peroxidase.

Reduce the accumulation of free radicals (ROS) that damage kidney cells.

> Reducing this free radical load helps kidney tissue recover and maintain its function better.

3. Improve blood circulation in the kidneys.

Resveratrol stimulates the production of Nitric oxide (NO) causes blood vessels in the kidneys to expand and improve blood flow.

> Resulting in a better supply of oxygen and nutrients to the kidney units (nephrons), which promotes increased glomerular filtration.

4. Balance blood sugar and fat levels.

In people with diabetes or hypercholesterolemia — which are the main causes of kidney disease — resveratrol helps.

increases insulin sensitivity

Reduce sugar and bad cholesterol (LDL) levels

> Makes the kidneys suffer less damage and able to recover from impaired functioning

5. Stimulates the cell life-prolonging gene SIRT1.

Resveratrol is considered a SIRT1 activator. This gene plays a role in regenerating and preventing cell degeneration.

> SIRT1 activation in kidney cells reduces apoptosis (cell death) and increases tolerance to hypoxia in kidney units.

Summary of overall results

When eating resveratrol extracted from mulberry continuously

Reduce inflammation and free radicals in the kidneys

Increase blood flow in the kidneys

Balancing sugar, fat, and blood pressure

Stimulates cellular regeneration mechanisms

> The sum of these mechanisms makes The glomerular filtration rate (eGFR) can significantly improve or delay kidney deterioration in the long term.