1. What causes the capillaries in the eye to break in the elderly?

1. What causes the capillaries in the eye to break in the elderly?

When you get older Structure of capillaries in the eye Will be more fragile due to many factors including:

1. Deterioration of blood vessel walls (Vascular aging)

Collagen and elastin in the blood vessel walls decrease. Loss of flexibility

There is an accumulation of free radicals. Makes the lining of the blood vessel walls (Endothelium) easily damaged

2. Congenital diseases in the elderly

High blood pressure → Increased pressure in blood vessels. Makes capillaries break easily

Diabetes → Causes Diabetic Retinopathy, blood vessel walls become thin and leaky.

Narrowed/hardened arteries from accumulated fat

3. Poor blood circulation

Platelets clump together abnormally.

Blood thickens from dehydration or high levels of fat in the blood.

4. Acute provoking factors

Cough or sneeze forcefully

Lift heavy things

Blood vessels burst from increased eye pressure, such as after cataract surgery.

2. Biological mechanism of resveratrol (extracted from mulberry) to protect and restore

Resveratrol is an antioxidant polyphenol. There is research supporting that it helps protect the vascular system and retina. The main mechanisms are

2.1 Prevent capillary deterioration

Antioxidant effect

→ Reduce damage to the lining of blood vessels from ROS (Reactive Oxygen Species).

→ Prevents chronic inflammation that causes blood vessel walls to thin.

Stimulates the production of nitric oxide (NO).

→ Expands blood vessels increase flexibility Reduce pressure in capillaries

2.2 Reduce inflammation (Anti-inflammatory effect)

Inhibits the NF-κB pathway → reduces the production of inflammatory substances such as TNF-α, IL-6.

Makes capillaries strong Reduce the chance of repeat breakage

2.3 Balancing blood clotting

Helps platelets not clump together too much → Reduces blockages that increase pressure in capillaries.

Makes the blood flow in the retina flow smoothly.

2.4 Protect retinal nerve cells (Retinal neuroprotection)

Stimulates SIRT1 pathway → Delays the death of retinal nerve cells.

Reduce the risk of age-related macular degeneration (AMD).

3. Results from using resveratrol on the problem of broken capillaries in the eye

Reduce the chance of repeated rupture of capillaries.

Restoring the strength and elasticity of blood vessel walls.

Slow down the deterioration of the retinal system.

Promotes overall eye health Suitable for elderly people who have cardiovascular diseases.

#ResveratrolDrVee