It has long been a matter of concern to me that smart Thai people still don't know about this. Or let's talk. Regarding strengthening the mitochondria
It has long been a matter of concern to me that smart Thai people still don't know about this. Or let's talk. Regarding strengthening the mitochondria
7 reasons supporting the credibility of articles published in PubMed that report Resveratrol is extracted from mulberry. (Mulberry-derived resveratrol) activates the longevity gene SIRT1 and stimulates the production of PGC-1α protein, which leads to strengthening of the mitochondria.
1. Published in the PubMed database.
PubMed is an academic database under the U.S. National Library of Medicine (NLM) that selects only peer-reviewed articles. (Peer-reviewed) makes published articles have high scientific credibility.
2. There is a reference to a confirmed biological molecular mechanism.
The paper clearly outlines the mechanism by which resveratrol stimulates SIRT1, a gene involved in longevity and protection against cell degeneration, and that SIRT1 stimulates the expression of PGC-1α, a transcriptional coactivator important for the formation of mitochondria.
3. The SIRT1 –> PGC-1α –> Mitochondrial biogenesis mechanism is accepted in the scientific community.
This mechanism has been validated at institutions such as Harvard, MIT, and NIH, with many studies showing that SIRT1 activation activates PGC-1α and leads to an increase in the number and quality of mitochondria.
4. Use mulberry extract directly (natural source validation)
The article states that Resveratrol is derived from mulberries. This eliminates doubts that the results are from synthetic chemicals or experiments in unnatural conditions. Promote the concept of using natural substances for health.
5. Tested in real biological systems (in vitro or in vivo)
Reliable articles often show results from cell lines or animal models showing that after exposure to resveratrol, SIRT1 and PGC-1α expression actually increased. with protein or mRNA level evidence
6. Based on previous research.
The article will include references to previous research, such as Dr. David Sinclair's extensive study of SIRT1 and resveratrol. It helps resveratrol trust that the guidelines used in the article are based on solid science.
7. The data is consistent with human trial results.
Many research articles on resveratrol have found that it has the effect of increasing cellular energy. Reduce organ deterioration and increases the durability of various systems, which is consistent with the effect of increasing the number of mitochondria through PGC-1α.