Clear and easy-to-understand explanations of biological mechanisms. about that Resveratrol is extracted from mulberry. Helps reduce the toxicity of...
Clear and easy-to-understand explanations of biological mechanisms. about that Resveratrol is extracted from mulberry. Reduces the toxicity of aflatoxin through strengthening the mitochondria:
Resveratrol from Mulberry Reduce aflatoxin poisoning By strengthening the mitochondria
1. What is aflatoxin?
Aflatoxin is a toxin from the Aspergillus family of fungi found in dried foods such as chili powder, dried chilies, coffee, spices, and grains.
Aflatoxin is Serious carcinogens and destroy DNA Including destroying the mitochondria in the cell.
2. What does resveratrol do?
Resveratrol is a polyphenol found in large amounts in mulberries. Has antioxidant properties and promote the activity of genes related to cellular energy, such as SIRT1 and PGC-1α
3. Mechanism: Strengthens mitochondria = prevents toxicity.
Resveratrol stimulates PGC-1α (Peroxisome proliferator-activated receptor gamma coactivator 1-alpha).
→ which controls the creation of new mitochondria in the cell. (mitochondrial biogenesis)
The result is:
Increase the number and quality of mitochondria
Increase energy production (ATP)
Increases the ability of cells to eliminate free radicals.
4. Effects on Aflatoxin:
When cells have healthy mitochondria:
can deal with oxidative stress caused by aflatoxin can be improved
Reduce DNA damage from aflatoxin poisoning.
Reduce the risk of cell mutation. which is the root cause of cancer
Summary:
Resveratrol extracted from mulberry protects cells from the toxic effects of aflatoxin. By strengthening mitochondria, increasing energy and protecting against free radicals.
Therefore, it is an important help in reducing the risk of contaminated food in the daily life of Thai people.