Preventing and treating stroke by strengthening mitochondria from resveratrol, which is extracted from mango...
Prevention and treatment of stroke by strengthening the mitochondria from resveratrol extracted from mulberry is based on several biological mechanisms related to mitochondrial function. (Mitochondria) and protecting the brain from ischemia or low oxygen levels. (ischemia/reperfusion injury) as follows:
Biological mechanism: Resveratrol and mitochondria in the prevention of stroke.
1.
Stimulates the creation of new mitochondria. (Mitochondrial Biogenesis)
Resveratrol stimulates PGC-1α (Peroxisome proliferator-activated receptor gamma coactivator 1-alpha), a key protein that stimulates cells to produce new mitochondria.
As a result, brain cells (neurons) have enough energy. Especially in conditions of brain ischemia.
2.
Increases the efficiency of mitochondrial function.
Resveratrol increases the production of ATP, the cell's main energy source.
Reduce electron leakage in the respiratory chain (Electron Transport Chain), reducing the creation of toxic free radicals.
3.
Reduce inflammation in the brain
Resveratrol inhibits the activity of NF-κB, which is a pro-inflammatory trigger.
Reduce levels of inflammatory cytokines such as IL-1β, TNF-α, which often spike in the period after stroke.
4.
Reduce damage from free radicals (Oxidative Stress)
Mitochondria are the source of free radicals in neurons.
Resveratrol has a direct antioxidant effect. and stimulates antioxidant enzymes such as SOD, catalase and glutathione peroxidase.
5.
Prevents the death of nerve cells. (Neuroprotection)
Resveratrol reduces apoptosis (programmed cell death) by reducing caspase-3 activity and protecting the structure of the mitochondria from collapse.
Prevents cytochrome c leakage from the mitochondria. which stimulates cell death
6.
Promote the circulatory system in the brain
Resveratrol improves blood vessel relaxation through the mechanism of Nitric Oxide (NO).
Increased NO reduces blood pressure. and prevent stenosis of cerebral blood vessels
Summary:
Strengthening your mitochondria with mulberry resveratrol helps:
Add energy to injured brain cells
Reduce inflammation and free radicals
Prevents the death of nerve cells.
Restoring nervous system function after stroke