Explains the superiority of resveratrol extracted from mulberry. Compared to resveratrol from synthetic chemicals and explain the biological mechanisms...
Explains the superiority of resveratrol extracted from mulberry. Compared to resveratrol from synthetic chemicals and explain biomolecular mechanisms The action of resveratrol in delaying aging
1. The superiority of resveratrol extracted from mulberry over synthetic resveratrol
1.1 Efficiency (Efficacy)
Resveratrol extracted from mulberries (Natural Resveratrol)
It is in the form of trans-resveratrol. (trans-Resveratrol), which is the most biologically active isomer in plants like mulberry. In addition to pure resveratrol, it also contains co-factors such as quercetin, rutin, and anthocyanins, which enhance the synergistic effect, helping resveratrol work better than alone.
Synthetic Resveratrol
get pure form But there are no natural substances involved. Makes the overall effect decrease Many experiments have found that Natural extracts are often more effective than isolated synthetic resveratrol.
1.2 Bioavailability
from mulberry There is a natural structure in the body. "Easy to identify and use" by binding to other molecules in fruit, such as natural sugars (glucosides) or certain types of fiber. Helps improve absorption and slow down the breakdown (metabolism), making the body absorb it longer.
from synthetic chemicals Pure resveratrol has a major problem with low bioavailability (<1%) and is metabolized very quickly in the intestines and liver to Glucuronides/Sulfates. that is not very effective Therefore, high doses must be used to achieve the same results as natural extracts.
1.3 Long-term Safety
from mulberry It has been consumed by humans for thousands of years in the form of fruits, food, and herbs. Research has found that it is safe even with long-term use. And there are also other phytonutrients. that helps prevent side effects
from synthetic chemicals There are still doubts about its long-term safety. This is because the body is not accustomed to high doses of pure isolates. There can be liver or kidney problems if used continuously and in excess.
2. Biological mechanisms of resveratrol in delaying aging
Resveratrol has profound effects on cellular mechanisms, the main ones being the following:
2.1 Stimulate SIRT1 (Sirtuin 1 Activation)
Resveratrol is an activator of SIRT1, a protein that acts Controls aging (Longevity Genes)
SIRT1 helps:
Extend cell life (Cellular Lifespan)
stimulate DNA repair
Reduce chronic inflammation (Chronic Inflammation)
Increase the efficiency of mitochondria (Mitochondrial Biogenesis) makes cells have more energy.
2.2 Inhibits the mTOR Pathway
mTOR is a protein involved in cell division and protein synthesis. Too much mTOR accelerates aging.
Resveratrol inhibits mTOR, similar to the effects of Caloric Restriction, which is proven to delay aging.
2.3 Reduce the creation of ROS (Reactive Oxygen Species)
Resveratrol is a powerful antioxidant that reduces ROS that causes damage to DNA, proteins, and cell membranes.
2.4 Promote Autophagy
Resveratrol stimulates the process of Autophagy, or the elimination of waste products in cells.
Makes cells clean, fresh and reduces the chance of chronic diseases such as cancer, Alzheimer's disease, cardiovascular disease, etc.
Simple summary:
> "Resveratrol from Mulberry Not just pure But it also comes with a natural partner that works together harmoniously, is well absorbed, works for a long time and is safer in the long run."