Compare resveratrol extracted from mulberry with sesamin extracted from black sesame seeds. Both biological mechanisms (Biological Mechanism) and ...

Compare resveratrol extracted from mulberry with sesamin extracted from black sesame seeds. Both biological mechanisms (Biological Mechanism) and research evidence databases, especially on Prevention and treatment of cancer

1. Biological Mechanism

Resveratrol (Resveratrol) is extracted from mulberry.

Substance group: Polyphenols (Stilbene Class)

Main mechanisms against cancer:

1. Stimulate SIRT1 (Longevity Gene Activator)

Helps repair DNA and protect cells from mutations.

2. Anti-chronic inflammation

Inhibits NF-κB and COX-2 → reduces the production of inflammatory substances that promote cancer.

3. Stimulate Apoptosis (Programmed Cell Death)

Activates Caspase-3 → specifically kills cancer cells.

4. Inhibits the formation of new blood vessels. (Anti-Angiogenesis)

Cuts blood vessels that feed cancer cells through reducing VEGF (Vascular Endothelial Growth Factor).

5. Antioxidant Power

Prevents DNA damage from free radicals (ROS).

Sesamin (Sesamin) is extracted from black sesame seeds.

Substance group: Lignans (phenolic phytonutrients)

Main mechanisms against cancer:

1. Antioxidants

Stimulates Nrf2 pathway → increases the production of enzymes to prevent cell destruction (SOD, Catalase, GPx)

2. Inhibits the growth of cancer cells

Sesamin inhibits cell cycle progression at G0/G1 Phase → slows down cell division.

3. Anti-inflammatory

Reduce the production of pro-inflammatory cytokines such as IL-6, TNF-α.

4. Stimulate Apoptosis

Has the effect of stimulating the Bax/Bcl-2 ratio → accelerating the death process of cancer cells.

5. Anti-metastasis

Inhibiting the movement of cancer cells (MMPs inhibition)

2. Compare the number of published research studies. (Only about cancer)

Topic Resveratrol (Mulberry) Sesamin (Black Sesame)

> Summary of numbers:

Research on resveratrol is approximately 20 times greater than on sesamin, especially research on Human cancer and clinic It is clearly superior.

Conclusion: Who is superior?

Resveratrol from Mulberry is outstanding in

Various mechanisms of cancer resistance

Preventing the spread of cancer

Stimulating cells to enter the anti-aging process

There is a lot of human research supporting this.

Sesamin from black sesame has advantages:

Enhance antioxidants

Reduce inflammation

Suitable for enhancing overall health. But there is also research on There is little protection against cancer in humans.

Short summary:

Resveratrol is more potent than sesamin. For the prevention and treatment of cancer both biological mechanisms and the quantity and quality of research supported