Resveratrol (resveratrol) is extracted from mulberry. Demonstrates superiority over sesamin (sesamin) extracted from black sesame seeds in many ways...
Resveratrol (resveratrol) is extracted from mulberry. Demonstrates superiority over sesamin (sesamin) extracted from black sesame seeds in many aspects of Prevent and treat cancer as follows:
1. Diversity of cancer types studied
Resveratrol: There is extensive research. Breast, colon, liver, lung, stomach, skin, prostate and brain cancers
→ Shows broad activity against cancer in many systems.
Sesamin: Effective in some cancers such as breast, white blood cell, kidney, and uterus, but studies are still limited.
Advantage: Resveratrol is superior in coverage for many types of cancer.
2. Entering human trial level
Resveratrol: There have been real human studies (such as a clinical trial to prevent colon cancer in high-risk groups), including use in supplement form.
Sesamin: There are no clear clinical studies on its anti-cancer use in humans.
Advantage: Resveratrol is more readily available for clinical development.
3. More complex and comprehensive mechanism of action
Resveratrol:
Inhibits NF‑κB, COX-2 (anti-inflammatory that promotes cancer)
Stimulates apoptosis (death of cancer cells)
Inhibits angiogenesis (creation of blood vessels to supply cancer cells)
Balancing autophagy (destroying abnormal cells)
Reverse chemoresistance
Sesame:
Some of the mechanisms are similar, such as inhibiting inflammation and stimulating apoptosis.
However, there is still no clear information regarding angiogenesis or reverse chemoresistance.
Advantages: Resveratrol has the potential to “Multiple blocks” in the cancer process
4. Preventive potential at the population level
Resveratrol from Mulberry There have been studies on antioxidant, antimutagenic, and photoprotective properties.
Sesamin, although it is high in antioxidants, has no information on its effects. photoprotection or defense oriented population-based
Advantage: Resveratrol plays a more “functional food” role.
5. Quantity and quality of research
Resveratrol: There are more international published studies, including meta-analyses and clinical trials.
Sesamin: Most of the research is still in laboratories and animals.
Advantage: Resveratrol is recognized and supported by world-class research institutes.
Conclusion:
> Resveratrol extracted from mulberry Demonstrates its superiority as an anti-cancer agent in terms of mechanism of action, studies in humans, and readiness for use in disease prevention and treatment compared to Sesamin from black sesame seeds