The Role of Resveratrol in Cancer Therapy

The Role of Resveratrol in Cancer Therapy

The role of resveratrol in cancer treatment

Abstract: Natural product compounds have received considerable attention from the scientific community for their potential effects on inflammatory diseases including cancer. A lot of research includes preclinical studies. Clinical and epidemiological studies indicate that the consumption of dietary polyphenols, found at high levels in cereals, vegetables and fruits, prevents the development of many diseases, including cancer. The development of cancer is a progression in which normal cells undergo genetic mutations. This causes the cells to continually grow, colonize and spread to other organs such as the liver, lungs, colon and brain. Compounds that modify the cancer process These are considered to be potential anticancer agents which may eventually allow for clinical application. natural resveratrol It is a phytoestrogen that has anti-oxidant, anti-inflammatory, and cardiovascular protective properties. and anti-cancer Resveratrol has been reported to reverse multidrug resistance in cancer cells and, when used in combination with clinically used drugs, can sensitize cancer cells to standard chemotherapy agents. Resveratrol has been developed with improved anti-cancer activity, bioavailability and pharmacokinetic profile. The current interest of this review is Resveratrol's in vivo and in vitro effects in a variety of cancers and intracellular molecular targets modulated by this polyphenol. It also comes with a comprehensive update of various clinical trials showing that it is a highly potent therapeutic and chemotherapy agent.