Molecular mechanisms of resveratrol in fighting cancer

Molecular mechanisms of resveratrol in fighting cancer

Resveratrol is a phytochemical that belongs to the stilbene family of plants. Many pre-clinical studies have investigated the anticancer properties of resveratrol. The molecular mechanism of resveratrol involves signaling pathways involving extracellular growth factors and tyrosine kinase receptors. Formation of multi-protein complexes and cellular metabolism. Cell proliferation and genome instability Cytoplasmic tyrosine kinase signaling (cytokines, integrins, and developmental pathways) Signal transduction by the transforming growth family-β superfamily. Apoptosis and inflammation Immune surveillance and hormone signaling Resveratrol has also shown a promising role in combating multidrug resistance. In the supplementary therapy together with 5-fluorouracil and cisplatin Resveratrol has a synergistic effect by increasing the sensitivity of cancer cells to chemotherapy. Resveratrol, which acts by multiple mechanisms simultaneously, has been highlighted as a promising anticancer agent with multiple targets. which is involved in both prevention and treatment of cancer