Preventing and treating cancer with resveratrol: from studies in mice to clinical trials in humans.

Preventing and treating cancer with resveratrol: from studies in mice to clinical trials in humans.

Abstract: Resveratrol (3,4',5-trihydroxy-trans-stilbene) is a polyphenol obtained from grapes, mulberries, peanuts, and certain plants. During the past decade Resveratrol has been shown to have pharmacological properties. From the biochemical properties and action of the molecule, from the effect of Resveratrol and cancer affects all three stages of carcinogenesis. It regulates cell division (initiation, promotion, and progression) by regulating signal transduction pathways that control cell division and growth, apoptosis, inflammation, angiogenesis. resveratrol (angiogenesis) and metastasis. Anti-cancer properties of resveratrol Confirmed ability to inhibit the proliferation of human cancer cells in vitro has led to animal studies. To evaluate the potential of this compound in cancer prevention and cancer treatment. To obtain comprehensive information from studies in rats with human cancer cells to study mechanisms related to the body's bioavailability, pharmacological effects, and feasibility studies of resveratrol. with clinical testing The conclusion describes directions for the future with resveratrol research. To be used as medicine to prevent and treat cancer.

Research was conducted at the Department of Pharmaceutical Sciences, Northeastern Ohio Universities Colleges of Medicine and Pharmacy, USA.