“The use of resveratrol in the fight against Cancer in women: a review” จากวารสาร Brazilian Journal of Health Review ...
Summary of the article “The use of resveratrol in the fight against Cancer in women: a review” from the Brazilian Journal of Health Review discusses the role of “Resveratrol (Resveratrol)” which is a polyphenol found in red grapes, mulberries and some plants. that it has the potential to help prevent and stop cancer in women especially breast cancer Cervical cancer and uterine cancer
The essence of the article
1. Resveratrol has many anti-cancer effects.
Research has gathered that Resveratrol can:
☆ Antioxidants Reduce DNA damage
☆ Reduce inflammation which is related to cancer.
☆ Inhibits the division of cancer cells.
☆ Stimulates the death of cancer cells (Apoptosis)
☆ Reduces the spread and creation of new blood vessels in cancer tumors. (anti-metastatic / anti-angiogenesis)
These mechanisms slow the growth of cancer cells in many organs of women.
2. Has a prominent effect in breast cancer
The article discusses data from trials saying Resveratrol:
- Reduce the increase in the number of breast cancer cells.
- Helps regulate cancer-related genes such as BRCA1 and BRCA2.
- Reduce resistance to certain chemotherapy drugs.
- Helps increase the efficiency of treatment in combination with other drugs.
- It also has an effect on regulating estrogen. which is related to breast cancer
3. Helps fight cervical cancer
Resveratrol has been found to:
- Reduce the activity of HPV E6/E7 proteins, which are the triggers for cervical cancer.
- Increases the activity of p53, which is a tumor suppressor gene.
- Stimulates the death of cervical cancer cells.
- The results of the study showed that the size of the tumor decreased after receiving Resveratrol.
Conclusion of the article:
The researchers concluded that resveratrol is a natural substance with "potential" to help prevent and enhance the treatment of cancer in women. through the antioxidant mechanism anti-inflammatory and stimulate the death of cancer cells