The role of resveratrol in cancer treatment

The role of resveratrol in cancer treatment

The Role of Resveratrol in Cancer Therapy

Resveratrol has been shown to reduce carcinogenicity in various stages, some of which are briefly described in Figure 2. Numerous in vivo and in vitro studies and Some clinical trials have shown evidence of resveratrol's great potential as an anticancer agent in both prevention and treatment of various cancers. Resveratrol has very low toxicity and, although it has multiple molecular targets, Protective pathways and common pathways that are often altered in cancer tumors This suggests that resveratrol is suitable for use as an anticancer agent and can also exert effective anticancer effects in combination with chemotherapy and targeted therapy. To prevent cancer including inhibiting oxidative stress, inflammation, and proliferation of cancer cells and stimulating cancer cell death mechanisms. In addition, resveratrol's poor bioavailability in humans is a major concern regarding the translation of basic research findings into treatment development, even though human clinical trials have produced positive findings. To increase the bioavailability of resveratrol and make it a potential drug, active research should focus on the formulation and optimization of resveratrol metabolism and the interactions of resveratrol with other compounds, as well as on the development of more bioavailable similar compounds.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751192/

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