Resveratrol is a regulator of cancer cell death (apoptosis) and Autophagy in cancer treatment

Resveratrol is a regulator of cancer cell death (apoptosis) and Autophagy in cancer treatment

Resveratrol as a modulatory of apoptosis and autophagy in cancer therapy

Cancer is the leading cause of death. It is a heavy economic and social burden for many countries. Despite great advances in cancer treatment But chemotherapy is still the most commonly used treatment. However, there are several side effects. including liver toxicity Kidney toxicity and toxic to the heart limits the effectiveness of conventional chemotherapy In recent years, natural products have gained attention as agents for treating diseases such as cancer. Resveratrol (RES), a naturally occurring polyphenol that occurs in some plants, has been used. It has the potential to prevent and treat various types of cancer. Resveratrol also helps reverse the negative effects of chemotherapy. In addition, resveratrol It can modulate cancer cell death and cancer cell autophagy is the main form of cancer cell death. by targeting various signaling pathways and up/down regulation of apoptotic and autophagy genes. This review summarizes the anticancer effects of resveratrol. and focuses on the basic mechanisms and targets for modulating cancer cell death and cancer cell autophagy by resveratrol.

https://link.springer.com/article/10.1007/s12094-021-02770-y

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