The role of resveratrol in cancer treatment

The role of resveratrol in cancer treatment

The Role of Resveratrol in Cancer Therapy

Recently, natural product compounds have received great attention from the scientific community for their potential effects against inflammatory diseases. including cancer The bulk of the research includes preclinical, clinical, and epidemiological studies. It states that the consumption of polyphenols found in certain plants Prevent various diseases including cancer The development of cancer is progressive. Normal cells undergo mutations in their genetic structure. This causes cells to continue to grow uncontrollably. and spreads to other organs such as the liver, lungs, colon, and brain. Compounds that modulate these carcinogenic processes can be considered as potential anticancer agents that eventually lead to clinical applications. Resveratrol, which is a natural stilbene, and flavonoid polyphenols. It is a phytoestrogen that has anti-oxidant properties. Anti-inflammatory, heart-protective and anti-cancer. It has been reported that resveratrol can reduce drug resistance in cancer cells. and when used in combination with drugs used in clinical practice It can make cancer cells more sensitive to standard chemotherapy drugs. Resveratrol has been developed with improved anticancer activity, bioavailability, and pharmacokinetic profile. The current focus of this review is on the in vivo and in vitro effects of resveratrol in a variety of cancers. and molecular targets in cells modulated by this polyphenol. It also comes with comprehensive updates of various clinical trials. This shows that the drug is a potential chemotherapeutic and preventative medicine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751192/

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